Retinic A10 Serum


With hydroxypinacolone retinoate – a gentle and safe, dermatologically tested, all-trans, direct retinoic acid

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OptoDerm Retinic A10 Serum contains 1% hydroxypinacolone retinoate (equivalent to approximately 17% retinol), belonging to a class of chemical compounds termed retinoids (derivatives of Vitamin A). It is capable of binding directly to retinoid receptors, without having to undergo enzymatic conversion steps and is therefore stronger than conventional retinoids, like retinol or retinol esters. ♦ It also contains the powerful anti-oxidant, alpha-Lipoic Acid.

The binding of retinoid receptors can enhance gene expression, which effectively turns key cellular functions on and off. When skin cell retinoid receptors are bound with retinoids, a cascade of mechanisms that benefit skin complexion are switched on. This results in enhanced cell proliferation, biosynthesis of extracellular proteins and glycans, and improved cellular turnover. These are important for normalizing cell renewal and repair processes.

♦ The mechanism of action of OptoDerm Retinic A10 Serum is advanced compared to other retinol derivatives. To interact with retinoid receptors, retinol must first be metabolised to more active forms, such as retinaldehyde and retinoic acid using several enzymatic steps. OptoDerm Retinic A10 Serum is unique in that it possesses innate retinoic activity, binding directly with retinoid receptors without the need for metabolic breakdown to more biologically active forms. Its efficacy is therefore much higher than higher concentrations of other retinoids (approximately equivalent to 17% retinol), without the irritation. It is dermatologically tested to offer less irritation potential than retinol, providing a gentle, safe and effective anti-aging retinoid.


Apply at night, after cleansing. Squeeze gently on the pump until drops appear on the tip. A little goes a long way. Avoid direct eye contact. Allow the serum to absorb for a couple of minutes after application and then apply other serums and creams as required. Works best when layered with OptoDerm Balance, Revive, Rejuvenate or Fade.

This product will make your skin more sun sensitive, so care should be taken to apply suitable >SPF30 creams


Water/Aqua/Eau, Lysolecithin (and) Xanthan Gum (and) Sclerotium Gum (and) Pullulan, Phosphatidylcholine, Hydrogenated Lecithin, Phospholipids, Ethoxydiglycol, Tocopheryl Acetate, Dimethyl Isosorbide, Hydroxypinacolone Retinoate, alpha-Lipoic Acid, Ethylhexylglycerin, Disodium EDTA, Phenoxyethanol

In the interests of producing the most effective products and keeping up with new generation actives, formulations and ingredients are subject to change without notice. The ingredients indicated on the product label are accurate as to the content of the product batch referred to

Shipping and Returns

  • Delivery is free for all orders over R800. Otherwise, delivery is R90 - R100 depending on the items you plan to purchase.
  • Once your product has shipped, it usually takes 3 - 5 business days within South Africa.
  • You can return your product up to 7 days after receiving your order. Please make sure that the products are not used or damaged and still in it’s original, sealed packaging

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